6K Annual New Cases of Major LARS with 45% Treated at Top 20
Well-Defined Disease and Pathophysiology
Severe LARS is characterized by maladaptive neural and tissue remodeling affecting motility and sensory pathways
- Easily diagnosed through validated LARS score
- Defined etiology, caused by rectal cancer surgery
- Chronic conditions with life expectancy of 15 years
No Non-Invasive Treatment Options Exist for Severe LARS
5-HT3R Antagonism is Clinically Validated for Severe FGIDs
